Abstract
Heat shock protein 27 is one of the members of the small heat shock protein family.Its molecular chaperone function and the interaction with the cell death pathway mediate cell survival under the stress state.The expression of heat shock protein 27 in ischemic lesions and remote areas and its changes in phosphorylation levels during cerebral ischemia is associated with neuronal tolerance to ischemia.However,the neuroprotective mechanism of heat shock protein 27 in cerebral ischemic tolerance still remains unclear.This article reviews the roles of heat shock protein 27 in cerebral ischemic tolerance and its potential mechanism. Key words: Heat-shock proteins; Brain ischemia; Ischemic preconditioning, Apoptosis
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
