Abstract

The interest of dermatologists in the study of zinc metabolism arose after the appearance of the article by Todd et al. (1934), in which it was indicated that a lack of zinc in the diet in rats leads to hair loss. Tucker (1955) and Dell (1958) in experiments on pigs and chickens not only confirmed the role of zinc deficiency in the genesis of alopecia areata, but also drew attention to the development of parakeratosis and histological changes in the mucous membrane of the esophagus.

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