Abstract
Abstract. The generalization of experimental and clinical data currently allows us to confirm the important pathogenetic role of vitamin K deficiency in cardiovascular calcification and atherosclerotic damage in chronic kidney disease (CKD). It was highlighted that, apart from vitamin K, the activity and expression of matrix Gla protein, which strongly inhibits vascular calcification, depended to a considerable extent on vitamin D. The efficacy and safety of the combined intake of vitamin K and D in slowing the progression of ectopic calcification, reducing cardiovascular risk, and improving prognosis in CKD patients need to be confirmed in multicenter randomized controlled trials.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
