The role of viral infection in the pathology of oral mucosa in persons with prosthetic constructions

Abstract

Aim.To detect viral infection of the oral mucous membrane in individuals with dentures.Material and methods.110 patients with removable and 100 - with fixed prostheses were examined. Diagnostics of virus infection were carried out by ELISA and PCR methods (Kvant-21).Results and discussion.It has been revealed that patients with removable prostheses revealed oral mucosa diseases in 91 (82,7%) persons and with fixed prostheses - in 75 (75,0%) patients. Viral infection in patients with removable dentures is detected in 58 (63.7%;91) and with fixed dentures in 43 (57.3%;75) patients. Among patients with removable dentures, HPV types 11 and 16 occur 1.3 times more frequently than in patients with fixed dentures, and HPV type 6 - 4.6 times less frequently. HPV types 11 and 16 are most frequently detected in patients with removable prostheses in the case of red lichen planus while in the group of patients with fixed prostheses they are more frequently observed in patients suffering from periodontal disease.Conclusion.Viral infection plays an important role in the development of diseases of the oral mucosa, which differ depending on the presence of removable and fixed dental structures. Papillomavirus types 6, 11, and 16 have the most pronounced effect on the course of oral mucosa diseases.