The role of vessel wall imaging in determining the best treatment approach for coexisting aneurysms and subarachnoid hemorrhage.

Abstract

The purpose of this study was to investigate the utilization of gadolinium enhancement on vessel wall imaging (VWI) in treatment decision-making for patients with two intracranial aneurysms presenting as a subarachnoid hemorrhage (SAH). We prospectively performed VWI using 3.0-Tesla (3T) magnetic resonance imaging (MRI) before treatment with endovascular coiling or surgical clipping in patients with one or two intracranial aneurysms. The VWI protocol includes three different scans: black blood (BB) T1-weighted, BB T2-weighted, TOF axial, and BB contrast-enhanced T1-weighted imaging. We analyzed all aneurysm ruptures both with and without gadolinium enhancement of the aneurysm wall. Thirty-eight patients with 48 aneurysms were enrolled in this study. Of these patients, 28 had a single aneurysm (15 ruptured and 13 unruptured), and 10 had two aneurysms and SAH (9 patients with two aneurysms and 1 patient with three aneurysms). Of the 15 single ruptured aneurysms, 12 (80.0%) showed positive wall enhancement, whereas 2 of the 13 single unruptured aneurysms (15.4%) demonstrated positive wall enhancement. Ten patients with SAH and two aneurysms showed wall enhancement of a single aneurysm, and these aneurysms were treated first. Gadolinium enhancement of an aneurysm wall on MRI was associated with aneurysm rupture. In patients with two aneurysms and SAH, this type of imaging can play an important role in determining the order of aneurysm treatment.