THE ROLE OF THYROID & PARATHYROID HORMONES IN PROSTHODONTIC TREATMENT- A NARRATIVE REVIEW

Abstract

Thyroid and parathyroid hormones play an important role in maintaining bone metabolism, which can have a direct effect on the health and stability of residual ridges, especially in edentulous patients. Preservation of residual ridges is critical to the success of dental prostheses such as dentures. Thyroid Hormones Thyroid is the major regulation of metabolism and effects all the bodily functions. Pituitary gland stimulated the thyroid to produce the hormones T4 – Thyroxine ; T3 – Tri iodothyrone and calcitonin. Thyroxine (T4) and Triiodothyronine (T3) hormones are important regulators of metabolism and influence the turnover of bone tissue by affecting the activity of osteoblasts and osteoclasts. a). Activation of osteoblasts: In particular, T3 increases the activity of osteoblasts, the cells responsible for bone formation. This can lead to an increase in bone density and strength, which is necessary to maintain the structure of the residual ridges. (b). Bone Resorption: Excessive levels of thyroid hormones (hyperthyroidism) can increase osteoclast activity, leading to accelerated bone resorption and possible bone loss, which can negatively affect residual ridges.[1]