Abstract
Thrombospondin-1(THBS-1), a kind of extracellular matrix proteins, whose biological action played an important role in corneal wound healing has became a research highlight.The currently research findings showed that THBS-1 could promote the healing of epithelium, stroma and endothelium through activating the transforming growth factor-β1(TGF-β1) which can accelerate cell proliferation, promote stroma forming and inducing cell migration.It is worthful in clinical treatment of al1 kinds of corneal wound healing.Now we summarized the research developments which have been acquired in the field recently in this article. Key words: Thrombospondin-1; Transforming growth factor-β; Corneal/wound healing
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