Abstract

T cells are a heterogenous group of cells and thus have multiple functions in the immune response. This multiplicity of functions has led to a multiplicity of names for T cell subsets; there are “killer cells,” “helper cells,” and “suppressor cells” implying that T cells kill foreign cells as well as help and suppress syngeneic effector lymphoid cells to perform their immunological functions. There have been a number of exciting basic discoveries made recently, which have significantly altered our understanding of how T cells perform some of these functions. These new insights should be helpful in designing experimental protocols to use the immune response to control cancer growth.

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