Abstract

Objective: Intrauterine under nutrition during fetal development is associated with an increased risk for cardiovascular and metabolic diseases in later life. Mechanisms responsible for these changes are thought to be the result of an unfavourable intrauterine programming of systems. We hypothesized that increased sympathic activity of the fetus persists postnatally and therefore may account for unfavourable adaptions of the cardiovascular system. Therefore we analyzed the sympathicus/vagus-system in growth retarded fetuses pre- and postnatally.

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