Abstract
ObjectiveNeonatal sepsis is a global public health concern in general and causes a massive burden in developing countries particularly in sub-Saharan Africa. Though it is mostly preventable, neonatal sepsis remained the leading cause of mortality in developing countries. This study was conducted to determine the current proportion and identify factors associated with neonatal sepsis to suggest directions.ResultsIn this study 504 randomly selected neonatal charts were reviewed. The proportion of overall neonatal sepsis was 63.69% (95% CI 59.38, 67.79), where early-onset sepsis was 59.33% (95% CI 54.96, 63.55) and late-onset sepsis was 4.17% (95% CI 2.73, 6.31). Maternal intra-partum fever, season of birth and admission, vaginal mode of delivery and preterm gestational age at birth increased the likelihood of overall and early-onset neonatal sepsis. In conclusion of this study, neonatal sepsis remaining the leading cause of morbidity among younger infants. Intra-partum conditions were major contributors to neonatal sepsis. Thus, providing emphasis on associated factors in particular and universal safe obstetric care in general is recommended.
Highlights
An estimated 2.8 million neonatal deaths occurred in 2013 and the mortality showed a rising trend from 2000 to 2013 [1]
Previous reports indicated that yearly cases of neonatal sepsis in sub-Saharan Africa ranged from 380,000 to 2,000,000 with annual related neonatal deaths of 270,000 [8, 9]
Maternal characteristics of neonates admitted in the neonates admitted in an intensive care unit (NICU) A total of 504 charts of neonates admitted in the NICU were reviewed
Summary
Maternal characteristics of neonates admitted in the NICU A total of 504 charts of neonates admitted in the NICU were reviewed. More than two-third (65.08%), of mothers gave spontaneous vaginal delivery and about 73% births occurred at Hospitals (Table 1). Neonates who were admitted during the dry and moist season from September to November were more likely to have both early-onset [AOR: 1.89, 95% CI (1.02–3.51)] and overall neonatal sepsis [AOR: 2.18, 95% CI (1.67–4.05)] as compared to June to August rainy season admissions. Neonates delivered vaginally were about 2 times [AOR: 2.22, 95% CI (1.24–4.32)] likely to have an early-onset and overall [AOR: 2.14, 95% CI (1.21–3.77)] sepsis. Neonates born before 37 complete weeks were likely to have early-onset [AOR: 5.03, 95% CI (3.04–8.33)] and overall [AOR: 4.03, 95% CI (2.43–6.71)] sepsis as compared to their counterparts (Table 3)
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