Abstract

Abstract Its acute leukemia, phagocytosis of Brucella organisms by mature neutrophils was not impaired. Phagocytosis of these organisms was not altered by antimetabolite therapy or during periods of bacterial infection. The absolute mature neutrophil count when infection developed was found to vary from patient to patient. The onset of bacterial infection in patients with acute leukemia was preceded by dynamic decreases in the number of mature neutrophils in the peripheral blood. Seventeen of eighteen patients had lower mature neutrophil counts immediately prior to the onset of infection as compared to the period free of infection. The median decrease was 54 per cent. As infection did not always follow decreases in mature neutrophils it is suggested that other factors also play a role in the development of bacterial infections in patients with acute leukemia.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.