Abstract

Cerebellar connections to frontal, prefrontal, and limbic structures underlie important cerebellar contributions to cognition, emotion, and affect. Evidence from anatomical, functional imaging, functional connectivity, and lesion studies all support not only a pronounced role for the cerebellum in normal cognition and emotion, but also possible pathogenic and therapeutic roles in patients with neuropsychiatric disease. The goal of this manuscript is to summarize current research on the role of the cerebellum and cerebellar circuitry in cognitive, emotional, and affective processing and the implications this has for the pathogenesis and treatment of neuropsychiatric disease.

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