Abstract

Malnutrition is a serious problem in post-stroke patients. Importantly, it intensifies with hospitalization, and is related to both somatic and psychological reasons, as well as is associated with the insufficient knowledge of people who accompany the patient. Malnutrition is a negative prognostic factor, leading to a reduction in the quality of life. Moreover, this condition significantly extends hospitalization time, increases the frequency of treatment in intensive care units, and negatively affects the effectiveness of rehabilitation. Obtaining growing data on the therapeutic effectiveness of new compounds of natural origin is possible through the use of pharmacodynamic and analytical methods to assess their therapeutic properties. The proper supply of nutrients, as well as compounds of natural origin, is an important element of post-stroke therapy, due to their strong antioxidant, anti-inflammatory, neuroprotective and neuroplasticity enhancing properties. Taking the above into account, in this review we present the current state of knowledge on the benefits of using selected substances of natural origin in patients after cerebral stroke.

Highlights

  • People with neurological diseases, including poststroke patients, are prone to malnutrition

  • This review presents the current state of knowledge about the benefits of supplementation in stroke patients

  • In patients with arterial hypertension, the level of Vitamin D (VitD) was not associated with the severity of stroke on admission and with poor functional results, but such a correlation was shown in the group of patients without hypertension (OD 5.51, 95% CI 95% 1.83–16.60 and OD 4.63, 95% CI 1.53–14.05) [15]

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Summary

Introduction

People with neurological diseases, including poststroke patients, are prone to malnutrition. According to ESPEN (European Society for Clinical Nutrition and Metabolism), malnutrition is defined as “a condition resulting from the lack of intake or absorption of nutrients, leading to a change in body composition, physical and intellectual impairment of the body’s physical and intellectual function, and adversely affecting the treatment of the underlying disease” [4]. Malnutrition is a negative prognostic factor, it significantly increases the risk of pressure ulcers and infections, in particular of the respiratory system, water and electrolyte disturbances, anemia, coagulation disorders, bradycardia, osteoporosis, leading to a reduction in the quality of life (Figure 1) This condition significantly extends hospitalization time, increases the frequency of treatment in intensive care units, and negatively affects the effectiveness of rehabilitation. This review presents the current state of knowledge about the benefits of supplementation in stroke patients

Natural Compounds
Vitamins
Flavonoids
Macroelements
Endogenous Substance
Other Bioactive Compounds
Conclusions
Findings
Literature
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