Abstract
The cancer incidence has risen dramatically over the last decades. About 8 million people died globally according to latest reports, which represented almost 40% more than it was 20 years ago. Risk factors for the development of cancer have been found to include smoking, alcohol, drugs, obesity and diet. Fiber intake has shown to exhibit chemoprotective effects on cancer proliferation and metastasis that may seem to be very promising. This article will review the role of different types of fiber such as, cellulose, lignin, pectin and inulin in development and prevention of different types of cancers. This article would also discuss the effectiveness of both types of fiber in cancer prevention.
Highlights
Cancer holds a significant burden in world disease prevalence
This study provides results contrary to the recent one, where a diet rich in dietary fiber is associated with a reduction in colon cancer risk [37], because butyrate (BT) is one of the main end products of anaerobic bacterial fermentation of dietary fiber in the human colon [38] that may affect colonic and fecal pH and contribute to antiproliferative activity [39]
This article concludes with a positive perception regarding the beneficial effect of dietary fiber for many common forms of cancer
Summary
Cancer holds a significant burden in world disease prevalence. As in 2010, there were 52.8 million deaths globally of which 8 million people died from cancer, which was 38% more than two decades ago [1]. We would try to define the different types of fiber, how they act as functional foods, and the mechanism that dietary fiber follows to increase apoptosis of cancer cells, and reduce tumorgenesis.
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