Abstract
Publisher Summary A short feedback mechanism may play a physiological role in the control of the secretion of the adrenocorticotropic hormone (ACTH). The existence of a control mechanism of the short type has been demonstrated for all the hormones manufactured in the anterior pituitary gland, as well as for the melanocyte stimulating hormone (MSH), which, in several species of animals, is secreted by the intermediate lobe. A short system is involved also in the control of the secretion of those pituitary hormones (growth hormone, prolactin, and MSH) that do not have a peripheral target gland and consequently are not regulated by traditional feedback mechanisms. In a study described in the chapter, ACTH proved effective in depressing blood corticosterone levels and in inhibiting the response to the mild stress, but only when placed in the median eminence (ME) region. Implants of ACTH in the frontal cerebral cortex or the pituitary were completely ineffective, as were implants of luteinizing hormone (LH) in the ME.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
