Abstract

Short chain fatty acids(SCFA) are metabolic products of the gut microbiota fermentation of dietary fiber, and are influenced by the structure and function of gut microbiota with the change of diet. Recent studies have indicated that SCFA may play an important role in the pathogenesis of type 2 diabetes mellitus, which is involved in the regulation of secretion of gut hormones, insulin sensitivity, glucose and lipid metabolism and so on. Further researches related to SCFA may provide a new measure and target to clarify the pathogenesis of type 2 diabetes mellitus as well as to prevent and treat it. Key words: Short chain fatty acids; Gut microbiota; Obesity; Metabolic syndrome; Type 2 diabetes mellitus

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