Abstract
The Role of Series Cholecystectomy in High Risk Acute Cholecystitis Patients Who Underwent Gallbladder Drainage
Highlights
Cholecystectomy (CCY) is the only definitive therapy for acute cholecystitis
recurrent biliary events (RBEs)-free survival was significantly better in the CCY within 2 months group (60% vs. 42%, p
In patients who accepted percutaneous transhepatic gallbladder drainage (PTGBD), the RBE and survival benefits of CCY within 2 months became insignificant in patients ≥ 80 years old or with a Charlson Comorbidity Index (CCI) score ≥ 9
Summary
We conducted this study to evaluate which patients may not benefit from further CCY after percutaneous transhepatic gallbladder drainage (PTGBD) has been performed in acute cholecystitis patients. After the diagnosis of acute cholecystitis, evaluations of the disease severity are necessary[9] to guide clinical management, such as early cholecystectomy (CCY) or percutaneous transhepatic gallbladder drainage (PTGBD), especially in critically ill patients[10, 11]. CCY is the only definitive therapy for acute cholecystitis[9, 17, 18], there are patients who cannot tolerate or do not want surgical intervention despite the benefits of early or delayed CCY. Patients with acute cholecystitis, who were successfully treated by PTGBD, should accept further early, interval, or delayed CCY to prevent future RBEs
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