Abstract

This review summarizes the results of recent studies in which the role of selenium has been addressed by investigating the functions and biochemical properties of mammalian selenocysteine-containing proteins and their involvement in maintaining the normal function of the male reproductive system. Selenium is an essential trace element; its deficiency leads to serious diseases, including male infertility disorders, prostate cancer, testicular cancer, etc. A total of 25 selenocysteine-containing proteins are known now, and almost half of them occur in the testis, highlighting the significance of the issue.

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