Abstract
Breast cancer is the most common cancer in women. About 70% of patients with advanced breast cancer willdevelop bone metastasis. Breast cancer bone metastasis is an important factor whichresultsin the poor prognosis. At present, there are many signaling pathways dicussed, among which the receptor acti-vator of nuclear factor-κβ/receptor activator of nuclear factor-κβligand/osteoprotegerin(RANK/RANKL/OPG)signaling pathway is crucial in the mechanism of breast cancer bone metastasis. This article aims to review the role of RANK/RANKL/OPG signaling pathway in the mechanism of breast cancer bone metastasis. Key words: Breast cancer; Bone metastasis; Receptoracti-vator of nuclear factor-κβ / receptor activator of nuclear factor-κβ ligand/osteoprotegerin
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
