Abstract
PurposePerformance of proton magnetic resonance spectroscopy (H-MRS) and apparent diffusion coefficient (ADC) values in the diagnosis of malignant thyroid nodules. MethodIn a retrospective study with malignant nodules of 14 patients, H-MRS and diffusion-weighted MR imaging (DWI) were performed. Choline (Cho) peak, Cho/creatine (Cr) ratio, and ADC values of malignant nodules were correlated with the five benign nodules and four normal-appearing thyroid lobe parenchymata. The gold standard reference was fine needle aspiration biopsy and histopathology. ResultsAt echo time 40–144-ms acquisitions, average Cho/Cr ratio for the malignant nodules was 2.95±1.54–5.30±2.38, cutoff values were >0.805 and >1.225, and ADC values were 0.06±0.02. ConclusionH-MRS acquisitions, DWI, and ADC mapping give diagnostic data about the nature of the nodules.
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