Abstract
Aim: The aim of our study was to compare the results of transvaginal ultrasonography (TVS) and final pathology in the determination of the depth of myometrial invasion in endometrial cancer preoperatively. Methods: The study was conducted as prospective observational study in a tertiary center between August 2012 -July 2012 and included 29 patients between the ages of 43 and 83 with endometrial biopsy results. Patients with endometrium cancer dignosis based on endometrial biopsy results were enrolled. Results: Transvaginal endometrial thickness was thicker for patients with myometrial invasion greater than � according to final pathology results, but this result was not statistically significant. When the patients were classified according to their surgical stages, 13 patients were stage 1a, 5 patients were stage 1b, 3 patients were stage 2, 6 patients stage 3, 2 patients stage 4. Final pathology of myometrial invasion greater than � patients compared with patients with thinner endometrium regarding age (p=0.003), gravidity (p=0.111), parity (p=0.135), weight (p=0.764), platelets (p= 0.831), CA125 (p=0.247) respectively. The age of patients were not statistically significant in comparison with tumor stage (p= 0.80). No statistical difference was observed when final pathology and transvaginal ultrasound results regarding myometrial invasion were compared (p= 1). We found that the sensitivity of preoperative transvaginal ultrasound for evaluation of myometrial invasion which is lesser than � was 77.7%. When final pathology and frozen section results were compared no significant statistical difference was found. (p=0.14). Conclusion: In our study, we compared the results of myometrial invasion in patients with pathologic and ultrasonographic findings and we found no statistically significant difference.
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More From: Journal of Controversies in Obstetrics & Gynecology and Pediatrics
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