Abstract
Results of our investigations suggest that potassium has a dynamic role in the regulation of blood pressure, as evidenced by the positive correlation between arterial content of potassium and the level of blood pressure. This relationship is influenced, however, by the content of sodium in arterial tissue. Thus, a relative excess of sodium depresses blood pressure, possibly through hydration of the arterial smooth muscle, the resulting dilution of contractile elements diminishing arterial tone. This explanation could account for our findings that the sodium-potassium ratio of arterial tissue uniformly shifts in opposite direction to the change in blood pressure level.
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