The Role of Platelet Rich Plasma Injections in Cases of Stress Incontinence

Abstract

Stress urinary incontinence is extremely bothersome and can lead to significant interference in the quality of life in the women. This study aims to suggest the role of platelet-rich plasma as a novel potential minimally invasive treatment for women suffering from stress urinary incontinence (SUI). In a prospective interventional study was conducted at Sayed Galal hospital on 20 patients seeking treatment for urinary stress incontinence were treated with autologous Platelet Rich Plasma injection at anterior vaginal wall, close to external urethral sphincter. Self-reported questionnaires were used to measure pre-treatment, 1 month and 3 months post-treatment symptom severity. The results are analyzed with valid statistical methods. Bivariate analysis revealed a significant incontinence improvement at both 1 month and 3 months post treatment without significant adverse reactions reported. No significant changes before and after the treatment were reported by the patients regarding sexual function by Female Sexual Function Index (FSFI) questionnaire. The result suggested that Local injection of autologous platelet rich plasma is a considerable treatment option in treating women with Stress urinary incontinence. It also opens up further research opportunities for autologous platelet rich plasma in clinical applications.