THE ROLE OF PHYSICAL ACTIVITY ON THE SUPPORT AND ENHANCE THE NATURAL BEHAVIOR OF STEM CELLS AND CHOSEN PHYSIOLOGICAL VARIABLES FOR PLAYERS ATHLETICS

Abstract

The CD34+ antigen is a single chain trans membrane glycoprotein, expressed on human hematopoietic stem and progenitor cells, endothelial progenitor cells, vascular endothelial cells, embryonic fibroblasts and some cells in fetal and adult nervous tissue. The antigen is absent in fully differentiated hematopoietic cells such as lymphocytes, monocytes and granulocytes, erythrocytes and platelets. Regular physical activity is related to lower rates of CVD, however the mechanisms underlying the benefits of exercise in the prevention of CVD are not fully clear. Exercise may improve the number (Laufs et al., 2005) and function (Hoetzer et al., 2007) of EPCS. The purpose of this study was to assess the effect of physical activity on the support and enhance the natural behavior of stem cell CD34+ in aerobic and anaerobic exercise bouts, also after an aerobic and anaerobic training programs and the effect on some physiological parameters. - Results showed that Vo2max increased in aerobic training program than anaerobic one, also in case of aerobic exercise bout compared to anaerobic one. - Lactate concentration was decreased in aerobic training program than anaerobic one, also in case of aerobic exercise bout compared to anaerobic one. - HB, RBCs, WBCs and hematocrit value was increased after aerobic and anaerobic training program and exercise bout. - CD34+ HPC counts were increased in peripheral blood of aerobic and anaerobic training program also in case of anaerobic exercise bout than aerobic one. CD34+ HPC counts are higher in athletes compared to control indicating adaptation induced exercise. Results: VO2 max was increased significantly in case of aerobic training program compared to anaerobic one (63±2.2 ml/kg/min) (55±2.1 ml/kg/min). Hematological values increased significantly in anaerobic program compared to aerobic, RBCs (5.5±0.3 and 4.8±0.2 Mil. /ul), WBCs (6.6±0.5 and 6.1±0.4 Thous/ul), HB (15.4±0.4 and 14.2±0.5 g/de) Hematocrit (4.6±1.2 and 4.4±1.1 %), CD34+ stem cells count increased significantly in case of anaerobic program than aerobic (259.6±21.65 and 131±14.63) and sedentary (173±24.11). These findings suggest that anaerobic training program provoke better adaptation to exercise and stem cell counts may differ between trained and sedentary Circulating immature cells are likely to be involved in angiogenesis and repair process, both mechanisms being associated with strenuous exercise, knowledge of the physiological of effects of training on stem cells might be of potential clinical use.