Abstract
The production of prodigiosin by non-proliferating cells of Serratia marcescens is inhibited by addition of glucose or different carbon sources to the induction medium. The induction in acidic external pH, mimicking the effects produced by the carbon sources, reduced prodigiosin synthesis, and the prodigiosin production seems to be related to the length of the low pH period. Buffering at pH 7·5 increased pigment production in media with repressing carbon sources. This study reveals that the inhibitory effect of carbon sources on prodigiosin production may be due to a lowering of the pH of the medium.
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