Abstract
We present a study on the influence of pH in the control of the surface density of ferritin-based iron oxide nanoparticles. It is found that at pH 3, the adsorption coverage of ferritin on the substrate is more than 1000 particles/μm2, owing to coulombic attraction between ferritin and the substrate. Upon increasing the pH to 9 and reducing the concentration, the surface density is reduced to as low as 2 particles/μm2, owing to coulombic repulsion. The average particle size is unaffected by the pH change.
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