Abstract
Irregular perturbations and convexity reversals in enzyme kinetic reactions are mathematically modeled by inhibition, catalytic, and rearrangement reactions. The convexity reversal model is especially interesting since it offers a simple alternative to the conformational argument of allosterism and the subunit coupling notion inherent to the Hill equation. Another unusual pattern, a cusp-like intersection on a fermentation hysteresis trajectory, is tentatively attributed to enzyme denaturation countering enzyme production. The role of convexity in reaction schemes where intermediate concentrations are not measured is also discussed. It is proposed that negative convexity in an early reaction rate transient is a clue to the presence of a shunting pathway in the chemical mechanism.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
