Abstract

The role of peripheral nerve injections in the diagnosis and treatment of CRPS

Highlights

  • It was Claude Bernard, a French physician and physiologist, who first correlated pain with sympathetic nervous system in the mid1800’s [1]

  • The first set of Complex Regional Pain Syndrome” (CRPS) clinical criteria that was developed is known as the Orlando or International Association for the Study of Pain (IASP) criteria, and its validation had been based on experience from other syndrome-defined diagnoses such as headaches and psychiatric disorders [10]

  • They note that CRPS-I nearly always follows injury to the deep tissues, which results in nerve injury and entrapment

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Summary

Introduction

It was Claude Bernard, a French physician and physiologist, who first correlated pain with sympathetic nervous system in the mid1800’s [1]. During the American Civil War, Mitchell noted that some soldiers developed a painful state after bullet injuries. In his reports, he described soldiers who experienced burning pain that never affected the trunk, rarely affected the thighs and arms, but often involved the legs and forearms, and mainly involved the hands and feet. A few years later, Mitchell coined the term “causalgia” (from Greek kausos fever + algia pain) to describe this condition [3]. Since these early reports, many terms such as Sudeck’s atrophy, sympathalgia and reflex sympathetic dystrophy have been used to describe this clinical scenario. In 1994, the Committee of Classification of Chronic Pain of the International Association for the Study of Pain (IASP) coined the term “Complex Regional Pain Syndrome” (CRPS) as a definitive nomenclature, with its typical subtypes: CRPS type I (where there is no obvious nerve damage) and CRPS type II (where there is identifiable nerve damage)

Symptoms of CRPS
Diagnostic criteria
Criteria type Clinical Research
Risk factors
Pathophysiology of nerve entrapments
The danger of misdiagnosis
Examples of nerve entrapment presenting as CRPS
Findings
Conclusion
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