Abstract
ObjectiveTo evaluate the accuracy of percutaneous transhepatic biliary biopsy (PTBB) in patients with suspected biliary obstruction.Materials and methods This was a retrospective analysis of 18 patients with obstructive jaundice who underwent PTBB. In each patient, three to ten fragments were collected from the lesion. The final diagnosis was confirmed in the pathology report. We also reviewed analyses of the results of laboratory tests performed before the procedure, as well as the Bismuth classification, clinical outcome, complications occurring during the procedure, access route, and materials used.ResultsTechnical success was achieved in 100% of the PTBB procedures. Among the 18 patients clinically diagnosed with bile duct stenosis, the pathological analysis confirmed that diagnosis in 17. In one case, the pathological findings were considered false-negative. The predominant tumor was cholangiocarcinoma (seen in 50% of the cases). Sixteen of the procedures (88.9%) were performed without complications. Transient hemobilia occurred in one case, and cholangitis occurred in another.ConclusionPTBB is a safe, viable, simple technique with a high rate of true-positive results for the definitive diagnosis of obstructive jaundice.
Highlights
Major advances in the diagnosis of biliary obstruction have been made in recent decades
Materials and methods: This was a retrospective analysis of 18 patients with obstructive jaundice who underwent percutaneous transhepatic biliary biopsy (PTBB)
Among the 18 patients clinically diagnosed with bile duct stenosis, the pathological analysis confirmed that diagnosis in 17
Summary
Major advances in the diagnosis of biliary obstruction have been made in recent decades. The site of obstruction in the biliary tract can be identified quickly and accurately through the use of imaging modalities such as ultrasound, computed tomography (CT), and magnetic resonance cholangiopancreatography (MRCP), all of which are noninvasive[1,2]. Tumors that affect the bile duct are often too small to be seen or to show specific image findings. Histological confirmation is often necessary in order to make the correct diagnosis, informing decisions regarding the treatment as well as the prognosis[1]. Interventional imaging techniques are gaining increasing prominence in the medical literature[4,5,6,7,8,9]
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