Abstract
The Role of Oxidative Stress in Cancer
Highlights
Oxidative stress refers to an often-dangerous disproportion between reactive oxygen species and the antioxidants that suppress them
While Reactive Oxygen Species (ROS) often take a significant amount of time to accumulate, once they have done so and are unable to be suppressed by cellular countermeasures, it is very likely for DNA damage to occur, and in cancerous cells, they enhance rapid proliferation, chronic inflammation, metastasis, and angiogenesis
Hydroxyl radicals can be produced as a result of the Fenton reaction in which iron donates an electron to hydrogen peroxide which is split into two hydroxyl radicals
Summary
Submission: March 10, 2020 Published: March 19, 2020 Volume 4 - Issue 2 How to cite this article: Krishna Dasari, Chikezie O Madu, Yi Lu. The Role of Oxidative Stress in Cancer.
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