Abstract

AbstractIn hemodynamics, perfusion pressure (PP) is the driving force for blood flow, determining the nutritive delivery of arterial blood to capillary beds. When describing blood flow for an organ, PP is generally expressed as the difference between the arterial and the venous pressure. In the eye, OPP is calculated as systemic blood pressure, which is a surrogate for ocular arterial pressure, minus IOP, which conventionally equals ocular venous pressure. There is increasing evidence on an association between low Ocular Perfusion Pressure (OPP) and glaucoma. Population‐based studies conducted in different geographical locations and in populations of different ethnic and socioeconomic backgrounds have consistently reported that low diastolic OPP is associated with the prevalence of OAG. In addition, low OPP at baseline presented with increased risk of developing glaucoma in incidence studies. The presentation will discuss whether the existing evidence could be translated in clinical practice and how further research could better define the role of OPP in glaucoma pathogenesis, risk factors assessment and management.

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