The Role of Nutraceuticals and Phytonutrients in Chickens' Gastrointestinal Diseases.

Abstract

Simple SummaryThe use of nutraceuticals and phytonutrients in poultry nutrition has been extensively explored over the past decade. The interest in these substances is linked to the search for natural compounds that can be effectively used to prevent and treat some of the main diseases of the chicken. The serious problem of antibiotic resistance and the consequent legislative constraints on their use required the search for alternatives. The purpose of this review is to describe the current status of the effects of some substances, such as probiotics and prebiotics, organic acids, vitamins and phytogenic feed additives, focusing specifically on studies concerning the prevention and treatment of four main gastrointestinal diseases in chicken: salmonellosis, necrotic enteritis (caused by Clostridium perfringens), campylobacteriosis, and coccidiosis. A brief description of these diseases and the effects of the main bioactive principles of the nutraceutical or phytonutrient groups will be provided. Although there are conflicting results, some works show very promising effects, with a reduction in the bacterial or protozoan load following treatment. Further studies are needed to verify the real effectiveness of these compounds and make them applicable in the field.In poultry, severe gastrointestinal diseases are caused by bacteria and coccidia, with important economic losses in the poultry industry and requirement of treatments which, for years, were based on the use of antibiotics and chemotherapies. Furthermore, Salmonella spp., Clostridium perfringens, and Campylobacter jejuni can cause serious foodborne diseases in people, resulting from consumption of poultry meat, eggs, and derived products. With the spread of antibiotic resistance, which affects both animals and humans, the restriction of antibiotic use in livestock production and the identification of a list of “critically important antimicrobials” became necessary. For this reason, researchers focused on natural compounds and effective alternatives to prevent gastrointestinal disease in poultry. This review summarizes the results of several studies published in the last decade, describing the use of different nutraceutical or phytonutrients in poultry industry. The results of the use of these products are not always encouraging. While some of the alternatives have proven to be very promising, further studies will be needed to verify the efficacy and practical applicability of other compounds.