Abstract
Hidradenitis suppurativa (HS) is a chronic inflammatory disease. Recently published studies have suggested the use of markers of inflammation to monitor HS patients. These studies discuss the platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), pan-immune-inflammation value (PIV), and systemic immune-inflammation index (SIII), which are also used in other inflammatory diseases. This study aimed to compare the blood parameters, including NLR, PLR, SIII, and PIV, in HS patients and healthy individuals, and determine their correlation with disease severity. The study included 81 HS patients and 61 healthy volunteers. The patients' medical records and laboratory values of the control group were reviewed retrospectively. HS severity was assessed using Hurley staging. NLR, PLR, SIII, and PIV values were calculated based on complete blood counts. NLR, SIII, and PIV values were significantly higher in HS patients compared to the healthy control group and were positively associated with disease severity. There was no significant difference observed in PLR values concerning disease severity. This study suggests that NLR, SIII, and PIV values can beutilized as simple and cost-effective tests to monitor disease activity and severity inHS patients. However, larger and more comprehensive studies are needed to establish diagnostic cutoff values, and further evaluation of sensitivity and specificity is required.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.