Abstract

Background: Schizophrenia (SCZ) is a psychiatric disorder with both altered neurodevelopmental and genetic components. Despite several studies performed, the SCZ etiology is still unclear. Altered blood and mRNA expression levels of brain-derived neurotrophic factor (BDNF), promoting synaptic transmission and neural plasticity, in the brain of SCZ patients and genetic analysis suggest contribution of BDNF to disease pathogenesis.

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