Abstract
Parkinson's disease (PD), the second most common neurodegenerative disease, is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the formation of intracytoplasmic Lewy inclusion bodies. To date, the diagnosis of idiopathic PD is mainly based on its cardinal clinical features: resting tremor, bradykinesia and rigidity. In recent years, advances in magnetic resonance imaging (MRI), transcranial sonography (TCS) and functional imaging - which includes positron emission tomography(PET)and single photon emission computed tomography (SPECT) - have provided new tools for the diagnosis of PD in its early stages and have discriminated it from other atypical Parkinsonian syndromes. This review focuses mainly on the current development of neuroimaging and its application in the diagnosis and differential diagnosis of PD.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
