Abstract

The Role of Neighborhood Social Characteristics on the Epigenome—Why the Lack of Investigations?

Highlights

  • For at least 20 years, phrases like cells to society and neurons to neighborhoods have been part of the scientific lexicon

  • This bridging of levels is why the study by Reuben and colleagues[4] makes an important contribution to the literature. These authors analyzed data from the Environmental Risk (E-Risk) Longitudinal Twin Study to ascertain whether neighborhood characteristics throughout childhood and adolescence were associated with DNA methylation at age 18 years

  • The authors found that children who grew up experiencing neighborhood social disadvantage have epigenetic profiles that are distinct from those of their peers who were raised in more advantaged settings

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Summary

Introduction

For at least 20 years, phrases like cells to society and neurons to neighborhoods have been part of the scientific lexicon. These authors analyzed data from the Environmental Risk (E-Risk) Longitudinal Twin Study to ascertain whether neighborhood characteristics throughout childhood and adolescence were associated with DNA methylation at age 18 years.

Results
Conclusion
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