The role of microwave ablation in treatment of small and medium sized hepatocellular carcinoma

Abstract

Back ground and aim of work: Microwave ablation (MWA) is effective and safe technique used in treatment of hepatocellular carcinoma (HCC). The aim of this study is to investigate the role of microwave ablation in treatment of small and medium sized hepatocellular Carcinoma. Methods: This prospective study included 50 patients who underwent microwave ablation for small and medium size hepatocellular carcinoma with abdominal ultrasound guidance. All patients' demographic, laboratory investigations and complications were recorded. To evaluate efficacy of microwave ablation, Contrast-enhanced computed tomography was done one month and repeated three months after the ablation. Results: Complete ablation of the tumor was done in 92% of small HCC patients (less than or equal 3 cm) whereas in 64% among medium size HCC patients (more than 3 and up to 4 cm). Tumor recurrence was recorded in one patient (4%) with medium size HCC. There was significant decline in serum alpha fetoprotein levels one month after ablation compared to before the procedure. No major complications of the procedure or mortality were reported. Conclusion: Microwave ablation is safe and effective in small to medium size HCC tumors treatment with no recorded major complications or mortality in addition to acceptable local tumor control.