Abstract
Schizophrenia is a chronic devastating psychiatric disorder, which severely damages public mental health. The pathophysiological mechanism of schizophrenia is complex and the etiology of schizophrenia is still unclear. Epidemiological study, twins study and family study show that genetic factors play a substantial part in the process of schizophrenia. Previous research indicates that there is a close association between microRNA-137 and schizophrenia, and that the ablation of microRNA-137 significantly affects clinical symptoms and prognosis of patients with schizophrenia. So it highlights the relationship between microRNA-137 and schizophrenia, which reveals its special role in the etiological mechanism of schizophrenia, and may provides new perspective about the treatment of patients in schizophrenia. Key words: microRNA-137; Schizophrenia; Single nucleotide Polymorphism
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