Abstract

The level of the transaminases in plasma and tissues, changes under various conditions of experimental and clinical stress and exercise as well as under pathological conditions. Andreotti et al. (1) reported transient increase in serum glutamic-oxalacetic (GOT) and glutamic-pyruvic transaminase (GPT) levels during a boxing match. Lending et al. (2) found that exposure of puppies under reduced atmospheric pressure conditions for 3 hr produced no significant effect on the plasma GOT level. Exposure to heat stress and muscular exercise also increased (3) the serum GOT and GPT levels of dogs as compared to their corresponding controls. Nerdrum and Berg (4) reported an increase in serum GOT level 10 min after brief exertion, falling to normal within 45 min. Vanlerenberghe et al. (5) found that rats subjected to hypoxia showed a marked increase in serum GOT and GPT levels.

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