The role of mechanical factors in the pathogenesis of short-term and prolonged spasm of the cerebral arteries.

Abstract

✓ The authors describe fibrous structures they name “chordae” that stabilize the position of arteries in cerebral subarachnoid spaces. The innervation of these structures and their relation to the innervation apparatus of the arterial wall is discussed. Animal experiments and human autopsy material were used to study the role of the stabilizing structures in the pathogenesis of arterial spasm following the rupture of saccular aneurysms. Mechanical stimuli produced short-term but not prolonged arterial spasm.