Abstract
The Role of Maternal Serum Triglycerides in Prediction of Large-For Gestational-Age in Pregestational and Gestational Diabetes Mellitus
Highlights
Still there is increasing tendency to macrosomia in fetuses of diabetic women despite good diabetic control
Decreased serum high-density lipoprotein Cholesterol (HDL-C) and increased serum triglycerides and cholesterol levels in pregnant women with PGDM and gestational diabetes mellitus (GDM) might chip in the evolution of fetal macrosomia or large for gestational age (LGA)
The intent of the current study was to assess the upshot of maternal lipids in the third trimester in predicting macrosomic newborns in pregnant women with pregestational and gestational diabetes and if there is preventive measures may be taken such as prepregnancy management of hyperlipidemia and proper diabetic control
Summary
Still there is increasing tendency to macrosomia in fetuses of diabetic women despite good diabetic control. Serum lipid metabolism is somewhat altered during pregnancy in diabetic women with increased serum maternal lipoprotein concentrations because of increased insulin resistance and lipolysis of peripheral adipose tissue [5,6]. Obstetric complications such as preterm delivery and preeclampsia were more frequent with this abnormal metabolism of lipid. The intent of the current study was to assess the upshot of maternal lipids in the third trimester in predicting (large-for-gestational-age) macrosomic newborns in pregnant women with pregestational and gestational diabetes and if there is preventive measures may be taken such as prepregnancy management of hyperlipidemia and proper diabetic control
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