Abstract
<h3>REPORT OF A CASE</h3> A 50-year-old white woman presented to our clinic for evaluation of a photosensitive skin eruption of 15 months' duration. The patient described a burning sensation after sun exposure, followed by persistent erythema. She practiced strict sun avoidance for several months before presenting to a local dermatologist. An evaluation revealed mild diffuse nonscarring alopecia, a positive antinuclear antibody titer (1:320), and a negative SSA/SSB titer. Laboratory studies revealed normal creatinine phosphokinase and aldolase values and a white blood cell count of 26×10<sup>9</sup>/L. A diagnosis of systemic lupus erythematosus was rendered, and treatment with hydroxychloroquine sulfate (Plaquenil) (200 mg twice daily) was initiated. The patient's eruption progressed, and mild dysphagia developed, with a 4.5-kg weight loss over the following 3 months. Her history revealed that she had undergone a partial colectomy followed by chemotherapy with fluorouracil and local irradiation for colon cancer (classification, Duke's B) 2
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