Abstract
Depression is a common mental disorder with high incidence rate and low remission rate.The prediction of therapeutic effect in depression is limited to clinical features and neuroimaging.Reviewed the results of magnetic resonance imaging for predicting the treatment response in depression and explored the objective image markers for predicting the therapeutic effect in depression. It showed that the studies mainly focused on emotion regulation neural circuitry and few on reward neural circuitry.Prefrontal cortex, cingulate cortex, amygdala and hippocampus play important roles on predicting therapeutic effect. The study of magnetic resonance imaging for predicting therapeutic effect in depression is a feasible research field.More researches of finding the role of reward neural circuits in predicting the effect of antidepressants are needed. The brain structure and function of the neural circuits involved in depression and predicting the effect of anti-depression need to be studied by multimodal MRI method. Key words: Depression; Magnetic resonance imaging; Efficacy; Prediction
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