The role of lipase in blood lipoprotein metabolism and accumulation of lipids in oocytes of the Siberian sturgeon Acipenser baerii during maturation

Abstract

Summary The purpose of this study was to investigate the role of lipoprotein lipase (LPL) and hepatic lipase (HL) played in accumulating lipid into oocytes and serum lipid metabolism in Siberian sturgeon Acipenser baerii. We determined ovarian LPL activity, serum LPL and HL activity, and several serum lipid amounts in different ovary development stages. Our results shown that LPL activity in ovaries during vitellogenesis, serum LPL and HL activity were increased during vitellogenesis with a significant high level in stage V, and decreased fast after ovulation. Serum very low density lipoprotein (VLDL), triglycerides (TG), and phospholipids (PL) concentrations were increased since stage II to IV, and then decreased till stage VI. Serum cholesterol (TC) and low-density lipoprotein (LDL) amounts were gradually increasing during ovaries development. Moreover, we found that serum two lipases activity positively correlated with serum VLDL, TG and, TC and negatively correlated with high-density lipoprotein (HDL). The variation tendency of serum LPL, HL activity and lipids concentration, and the close correlationship between the two lipases and lipids during ovarian development suggest that LPL and HL participate in regulating blood lipid metabolism.