Abstract
The mechanical deformability of the cytoplasm is a key determinant of several fundamental cellular processes, including mechanotransduction, migration, and organelle positioning. Consequently, changes in the cytoplasmic mechanical properties are correlated with diseases, such as cancer, muscular dystrophy, and premature aging. While the mechanical deformability of the cytoplasm has been well-studied in vitro using tissue culture cells, much less is known about the in vivo biophysical properties of the cytoplasm.
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