Abstract
Primary and metastatic liver tumors are an increasing global health burden. As of 2020 colorectal cancer (CRC), which often presents with hepatic metastasis in the course of the disease was a second leading cause of cancer-related mortality worldwide. This was followed by hepatic cell carcinoma (HCC). Besides systemic therapies and surgical methods, which are not always applicable, many locoregional approaches were developed and are being increasingly implemented in the field of interventional radiology (IR) – both as primary and bridging procedures.
 The purpose of this article is to outline and briefly discuss these primary approaches used in IR in liver neoplastic disease.
Highlights
Primary liver malignancies and hepatic metastasis are an increasing global health burden
As of 2020 colorectal cancer (CRC), which often presents with hepatic metastasis in the course of the disease was a second leading cause of cancer-related mortality worldwide
This was followed by hepatic cell carcinoma (HCC)
Summary
Primary liver malignancies and hepatic metastasis are an increasing global health burden. Colorectal cancer (CRC), which often presents with liver disseminated process throughout the course of the disease was a second leading cause of cancer-related mortality as of the year 2020. This was followed by primary hepatic malignancies mainly in the form of hepatocellular carcinoma (HCC) (1). Many patients present with nonresectable lesions or significant contradictions, which disqualify them from classic approach. This created a need for other less invasive procedures
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