The role of integrated myocardial management in reoperative coronary surgery.

Abstract

This article identifies the effect of integrated myocardial protection on outcomes after first-time repeat coronary artery bypass grafting (CABG). A consecutive series of 124 repeat CABG procedures were performed between January 1996 and December 1999 with single aortic cross-clamping for all anastomoses and integrated myocardial protection. This included ischemia for heart dissection and distal grafting, and perfusion throughout the remainder of aortic clamping (including warm/cold, substrate/nonsubstrate-enhanced blood cardioplegia, delivered antegrade/retrograde, continuously/intermittently). Mean patient age was 67 +/ - 10 years (median 68) with 61% in New York Heart Association class IV and 23% in class III. Mean ejection fraction (EF) was 45 +/- 10.6% with EF 40% or less in 33% of patients and 30% or less in 20%. An average of 2.5 +/- 0.9 grafts were constructed. Cross-clamp times averaged 72 +/- 22 min and cardiopulmonary bypass time averaged 91 +/- 27 min. The average time from release of cross-clamp it disconnection from cardiopulmonary bypass (CPB) was 10 min. Median postoperative hospital stay was 6 days. hospital mortality was 2.4%, intra-aortic balloon pump (IABP) use 3.2%, stroke 0.8%, atrial fibrillation 11%, and reexploration for bleeding 2.4%. Integrated myocardial protection with blood cardioplegia is safe during reoperative coronary surgery. It allows rapid separation from CPB, limited IABP use, and low morbidity and mortality.