Abstract
Mucosal surfaces, which are frequently exposed to external antigens, are a major part of the immune system. The development of oral tolerance is a result of a complex interplay between a variety of innate and adaptive immune functions; deficiencies in these mechanisms may contribute to the development of allergic disorders. Although regulatory T cells have a clear role in enforcing oral tolerance, the role of the dominant immunoglobulin in the gut, immunoglobulin A (IgA), is less clear. This perspective will focus on IgA and its role in tolerance to oral antigens and the development of food allergies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
