Abstract
The role of hepatic resection for gastric cancer liver metastases – literature review
Highlights
Gastric cancer is one of the most commonly encountered malignancies worldwide and an important cause of cancer related death [1]
In such cases the most commonly encountered patterns of spread are represented by peritoneal dissemination leading to the development of peritoneal carcinomatosis, lymphatic dissemination leading to the development of lymph node metastases and hematogenous dissemination leading to the apparition of parenchimatous metastases
The role of surgery for gastric cancer liver metastases has been investigated in studies which were focused on the issue of hepatic resection for non-colorectal liver metastases; in the study conducted by Slotta et al, 14 patients with metachronous liver metastases were included [3]
Summary
Gastric cancer is one of the most commonly encountered malignancies worldwide and an important cause of cancer related death [1]. The role of surgery for gastric cancer liver metastases has been investigated in studies which were focused on the issue of hepatic resection for non-colorectal liver metastases; in the study conducted by Slotta et al, 14 patients with metachronous liver metastases were included [3]. Among these cases, the author reported a median overall survival of 17.3 months after liver resection with curative intent, significantly higher when compared to data reported so far for patients submitted to systemic chemotherapy [3]. Patients submitted to surgery for metachronous lesions seemed to have better outcomes when compared to cases submitted to surgery for synchronous lesion; the presence of extrahepatic disease seemed to have a negative influence of survival; this fact did not reach statistically significant influence [7]
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