Abstract
Animals were injected with lithium chloride or physiological saline on four occasions prior to a single conditioning trial on which the taste of saccharin was followed by the injection of lithium chloride. On a subsequent two-bottle test for aversions to the saccharin water, it was found that animals preexposed to the lithium chloride formed weaker aversions than did animals preexposed to the physiological saline. Weakened aversions occurred independent of the amount of handling animals had experienced prior to the preexposure phase of the experiment. These findings indicated that experimenter-generated handling cues did not appear to play a role in mediating the treatment preexposure effect.
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